Response to R-warfarin anticoagulant effect

Potentiation of the anticoagulant effect of warfarin.

Accepted 29 March 1996 A 63-year-old woman with longstanding rheumatoid arthritis was receiving warfarin therapy for an aortic valve replacement. The dose of warfarin was monitored via a hospital anticoagulation clinic and remained stable at 4-4.5 mg per day with no significant bleeding or thrombotic episodes. In September 1993 the patient began attending a general-practice-based anticoagulatio...

Discovery of Anticoagulant Warfarin.

Leflunomide can potentiate the anticoagulant effect of warfarin.

Effect of Left Ventricular Systolic Dysfunction on Response to Warfarin.

Candidates for chronic warfarin therapy often have co-morbid conditions, such as heart failure, with reduced left ventricular ejection fraction. Previous reports have demonstrated an increased risk of over-anticoagulation due to reduced warfarin dose requirement in patients with decompensated heart failure. However, the influence of left ventricular systolic dysfunction (LVSD), defined as left ...

Evaluation of the Effect of Lime Fruit Juice on the Anticoagulant Effect of Warfarin

AIM Citrus aurantifolia (Family Rutaceae) is commonly known as a familiar food and medicine, and s therapeutic effectiveness in a variety of diseases has been suggested in traditional medicine. Various complementary and alternative medicines (CAM) have been shown to interact with orthodox medicines. Hence, the aim of this study is to investigate such a phenomenon particularly the interaction of...